Botox, Dysport, Xeomin, Jeuveau, Daxxify, and Letybo: Understanding Your Options

“Botox” is often used as a general term for wrinkle-relaxing injections, but it is one brand within a larger group of botulinum toxin type A products.

Other US-approved cosmetic options include Dysport, Xeomin, Jeuveau, Daxxify, and Letybo. They share a basic mechanism, but their formulations, dosing, approved indications, and supporting studies differ.

What do they have in common?

These products temporarily reduce muscle activity by inhibiting the release of acetylcholine, a chemical messenger involved in muscle contraction.

When appropriately selected and placed, treatment can soften certain expression lines. The result depends on your anatomy, muscle activity, dose, placement, and goals—not simply the brand name.

Botox Cosmetic

Botox Cosmetic contains onabotulinumtoxinA and has a long history of cosmetic use.

It is important to distinguish its cosmetic labeling from the separate medical indications associated with Botox. Approval of one product for a particular use does not apply automatically to every botulinum toxin.

Dysport

Dysport contains abobotulinumtoxinA. Its formulation and dosing differ from Botox Cosmetic.

Claims that it always spreads better or produces more natural movement oversimplify treatment. The area affected depends on factors including dose, injection volume, placement, and anatomy.

Xeomin

Xeomin contains incobotulinumtoxinA. Its manufacturing process removes accessory complexing proteins.

That does not mean the vial contains only the active toxin or has no other ingredients. It also does not establish that it is universally safer, more effective, or more suitable than another product.

Jeuveau

Jeuveau contains prabotulinumtoxinA and is another option for cosmetic treatment.

A recommendation should be based on the patient, treatment goal, and product evidence. Broad claims that a brand produces inconsistent results are not a useful substitute for that assessment.

Daxxify

Daxxify contains daxibotulinumtoxinA and uses a peptide-containing formulation rather than human serum albumin as its stabilizer.

Its glabellar-line studies support a longer duration for many patients, but an individual’s result cannot be guaranteed. Findings from the area between the eyebrows should not automatically be applied to every other treatment location.

Letybo

Letybo contains letibotulinumtoxinA and received FDA approval in 2024 for temporary improvement of moderate to severe glabellar lines in adults.

Its inclusion in the US market is an important update to older brand overviews. Approval does not mean it is offered at every practice.

Units are product-specific

Botulinum toxin units are not interchangeable between brands. Comparing price per unit without understanding the product and proposed treatment can be misleading.

Your provider should explain which product is being used, why it was selected, and the total treatment cost.

Which should you choose?

At Modern Aesthetics in San Jose, I offer Botox, Dysport, and Daxxify. I consider your previous response, muscle activity, treatment area, goals, and preferences when discussing options.

All botulinum toxin products carry risks and require medical screening. Schedule a consultation to discuss an individualized plan rather than choosing by brand reputation alone.

Updated October 23, 2026.

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Where Can Botox and Other Wrinkle-Relaxing Injections Be Used?

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Neurotoxins: What are they & how do they work?